I have to echo this sentiment here. Every time I see a post about PyPy being fast, I think, "Hmm, perhaps I should try out this package I'm working on and see if it performs better." After getting a PyPy environment working---sometimes by installing forks that are PyPy compatible---I almost always end up with real word uses that are noticeably slower with PyPy as opposed to regular ol' CPython.

I may not be coding to PyPy's strengths, but I've gone through this process on several different packages that I've released and I tend to see similar results each time. I want to try and use PyPy to make my code faster, but it just doesn't seem to do it with real code I'm using.