These problems are hard, but have already been solved. The B-1 Lancer has active turbulence reduction built into the airframe, via the small canards on its nose. https://ntrs.nasa.gov/citations/19840005129
It's designed to work at Mach 0.85, and was meant to increase the lifespan of the airframe during low-altitude penetration flights where lots of turbulence could be expected.
Do you have a feel for how the maneuverability of a B-1 being controlled by the canards compares to that of a typical airliner?
It seems like a system like this would need to respond very quickly to changes in the air mass, and the weight and slow response of an airliner might make this system less feasible unless you could somehow measure airflow a reasonable distance in front of the plane.
It's designed to work at Mach 0.85, and was meant to increase the lifespan of the airframe during low-altitude penetration flights where lots of turbulence could be expected.