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While we're at it, here's an assessment of many drugs significantly affected by your CYP1a2 genotype: https://onlinelibrary.wiley.com/doi/full/10.1111/j.1742-7843...

I'd recommend checking out your CYP2D6 too. Proper recommendations haven't yet reached the clinic, so if you want personalized medicine then you'll have to educate yourself. Caveat, for dozens of reasons, differing genotypes won't necessarily affect drug pharmacokinetics, even if the metabolic pathway suggests it should.

Liver enzymes are cool.



> I'd recommend checking out your CYP2D6 too.

I have the nonfunctional genotype: Some effects. I can't metabolize codeine into its active drug, so it's just a trash useless drug to me that was prescribed a few times in the past to no effect. Additionally, DXM cough meds stays with me a crazy long time so I have to increase dosage interval else I get high off it. No doubt affects other common medications.

There is a test: https://en.wikipedia.org/wiki/AmpliChip_CYP450_Test if anyone knows more the Wikipedia page needs updating. Maybe there's more tests now. Just seems crazy none of these tests seem to be routine yet to keep in patient file. This is not 'new' stuff anymore.


>Proper recommendations haven't yet reached the clinic

Completely agree. I've seen four cardiologists, two nephrologists in my years of dealing with high blood pressure.

They basically just mix and match different BP drugs, hoping something works.

It's out of the stone age.




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