Having been vaccinated for Tdap recently very reliably predicts a 40% lower risk of dementia.
I gather flu vaccine has similar effect size. Nobody knows why. Ask, and people speculate about inflammation.
Having been treated for herpes lately -- valacyclovir, lately -- seems too to have outsize effect. I get all three.
People doing autopsies say brains they examine are very often laced with herpes virus and bacteria, vs. doctrine that insists nothing gets in.
US grants $2B annually to study plaque formation in transgenic mice. Approximately none of it goes for anything of value. When the amyloid boat sinks, a lot of biochemists will need to find something else to do. They would better look early.
I'm young (early 30s) but have a strong family history of late onset Alzheimers (my father, and both of my mother's parents).
I also get cold sores on occasion. I've brought this -- and the HSV-Alzheimers connection -- up to my doctor and a nurse, but neither had heard of the connection before (but I directed them to [0]), or thought it was worth pursuing anything like valacyclovir.
Roughly, the sentiment was that I am young and have time to wait for more research, that taking drugs long term will itself likely have consequences.
I'm not inclined to disagree there, although the evidence seems quite strong.
I look forward to seeing more funding and scientific effort directed toward other avenues.
I gather flu vaccine has similar effect size. Nobody knows why. Ask, and people speculate about inflammation.
Having been treated for herpes lately -- valacyclovir, lately -- seems too to have outsize effect. I get all three.
People doing autopsies say brains they examine are very often laced with herpes virus and bacteria, vs. doctrine that insists nothing gets in.
US grants $2B annually to study plaque formation in transgenic mice. Approximately none of it goes for anything of value. When the amyloid boat sinks, a lot of biochemists will need to find something else to do. They would better look early.