I can say for certain that the demand for solid .NET devs is really high in the Philadelphia area right now. I am constantly bombarded from recruiters, and now even old employers that are offering me new positions. Beyond this, I've actually gotten a chance to look at some resumes over the last 2-3 months and it seems that the typical applicant who gets at least a decent consideration isn't even all that skilled or experienced.
On the other hand, when I was searching for a new position some 7 to 8 months ago, the few python places here seemed to have unrealistic expectations of their applicants.
The exact same in Minneapolis. I'm definitely not learning Python for a job—it's strictly for fun side projects, which you really don't get in either .NET or Java. The main reason I'd avoid those languages would be to avoid mercenary programmers, and instead find a dev who gives a shit.
Choice quote (paraphrased) from a .NET dev: "who cares what the code looks like, you should be gone by the time anyone would look at it."
On the other hand, when I was searching for a new position some 7 to 8 months ago, the few python places here seemed to have unrealistic expectations of their applicants.