I would argue it is a breach of the initial options agreement (at least in spirit). Those shares were negotiated under a set of conditions- the stock was very risky, and as a result worth very little. Now that everything has turned out well, you can't go back and say, "Wait, I didn't think it would be worth this much - give it back.". Pincus wouldn't be going back after a failed venture and forking over huge amounts of cash to compensate for worthless stock, now, would he?

The option price and amount was set previously, and should be honored as long as the employee is performing their duties reasonably.

This is greed in it's simplest form.