One of the biggest problems I've found with working from home is that your work life and your professional life start to blend together in unfortunate ways. Working without office space is common in pre-startups and it's dreadful. I've been told that blending your work and professional life is simply foolishness on an individual level. Usually this isn't the case. The circumstances tend to be different and there's a lot of pressure to compress your life like this. It's dreadful. Everything feels like work after awhile. Other people I've spoken to in the startup/entrepreneur scene who work from home have conferred this sentiment. It's often the case that the lifestyle work from home produces is unsustainable in the long run. In this way it is a degenerate lifestyle. It's challenging to turn a home into a proper workspace.

A rebuttal to those who dislike the office. I would argue that the many of the downsides of the office tend to be blessings in disguise. You aren't meant to be totally comfortable at work. Going to the office is like a performance. You aren't meant to be totally comfortable while performing a duty. It's like doing a presentation. You shouldn't go up on stage and let it all hang loose. The office space tends to cultivate the right things for working which are not the right things for relaxed living.