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This is key.

Apoe status appears to control the absorption rates of LDL cholesterol (tiny balls of fat).

Individuals with apoe4, appear to have really low LDL cholesterol absorption rates between cells, and high blood-LDL cholesterol concentrations.

Having done a bit of research on optimal dieting, its pretty inconclusive.

This study shows negative consequences resulting from high fat diets for apoe4: https://www.ncbi.nlm.nih.gov/pubmed/27656136



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