I'm very much not saying that's what it is. Looking at the end it looks like an encoded zip file which the code extracts. Perhaps somebody else will be kind enough to run it and find out what it does. I'd feel too guilty, having told too many people not to do that.
Because it happens to use a base64-encoded string to obscure some of what it's doing? Yes, there's malware which does that, but this is also such an ancient trick in humorous code obfuscation that it seems silly to jump to the level of paranoia you're displaying (especially given that A) it's by a well-known member of the Python community and B) it was published April 1).
I'm very much not saying that's what it is. Looking at the end it looks like an encoded zip file which the code extracts. Perhaps somebody else will be kind enough to run it and find out what it does. I'd feel too guilty, having told too many people not to do that.